Oméga 3 Marin provides
long-chain omega-3 fatty acids directly from fish oil. A serving of
6 capsules provides
3,000 mg of wild anchovy oil, including
540 mg of EPA and 360 mg of DHA. The total intake therefore reaches
900 mg of EPA and DHA per day, in a
3:2 ratio.
EPA and DHA can be produced from alpha-linolenic acid found in certain plants, but this conversion remains limited, particularly for DHA. Their
direct intake through oily fish or marine oils therefore immediately provides the body with the two forms used by its cells. ANSES establishes a daily nutritional reference of
250 mg for DHA and 250 mg for EPA in adults. A full serving of Oméga 3 Marin
exceeds both reference values.
EPA and DHA: components of cell membranesAfter consumption, the oil is dispersed by bile and then digested by enzymes. EPA and DHA are
absorbed with other dietary lipids, transported in the bloodstream and gradually
incorporated into cell membranes.
Their long chains, rich in double bonds, provide
flexibility to membranes. This property facilitates the function of numerous receptors, channels and proteins responsible for transmitting signals between cells.
Their incorporation is not immediate: it develops gradually with
regular intake. This is why
continued consumption is more consistent than occasional use when seeking to maintain omega-3 status.
A combination that supports the heartEPA and DHA work together in
heart muscle cells. Their presence in membranes contributes to the exchange of ions such as sodium, potassium and calcium, which are necessary for coordinated heart contractions. They also act as precursors to various
lipid messengers involved in the normal regulation of vascular and inflammatory responses.
EPA plays a particularly important role in the production of these lipid mediators. DHA, which is longer and more flexible, has a greater influence on the physical properties of membranes. Their
complementarity explains why the European heart-related claim concerns their combination.
EPA and DHA contribute to normal heart function from a
daily intake of 250 mg. Even the minimum intake of
3 capsules per day provides, by proportional calculation,
450 mg of EPA and DHA. The threshold associated with the heart claim is therefore reached across the entire recommended range of use.
DHA, a structural fatty acid in the brainDHA is particularly abundant in
neuronal membranes. Its highly flexible structure helps these membranes retain the properties required for receptor function, signal transmission and exchanges between nerve cells.
It therefore contributes to maintaining a
membrane environment suited to communication within the brain. It does not act as a temporary stimulant: its role is primarily structural and forms part of the normal maintenance of nervous tissues.
DHA contributes to
normal brain function when daily intake reaches
250 mg. A full serving of 6 Oméga 3 Marin capsules provides
360 mg of DHA and therefore meets this condition.
Nutritional support for visionThe retina is also very rich in DHA, particularly in the
photoreceptors responsible for converting light into a nerve signal. The flexibility of DHA-rich membranes facilitates changes in the shape of visual proteins and the transmission of information to the brain.
With
360 mg of DHA per 6 capsules, our product also reaches the 250 mg threshold associated with the
maintenance of normal vision. This officially recognised function of DHA complements the formula’s benefits for the brain and heart.
Oil from wild anchoviesThe primary producers of EPA and DHA in the marine environment are
microalgae. These fatty acids then travel through the food chain and accumulate in fish tissues.
Anchovies, small pelagic fish, are therefore a
natural source of marine omega-3s.
Formula features •
Oil sourced from wild anchovies;
•
3,000 mg of oil per 6 capsules;
•
540 mg of EPA and 360 mg of DHA;
•
900 mg of combined EPA and DHA in a full serving;
•
EPA/DHA ratio of 3:2;
•
a sufficient dose for the heart claim from the minimum intake;
•
a full dose that meets the conditions for brain- and vision-related claims;
•
adjustable dosage of 3 to 6 capsules per day;
•
format of 200 capsules.
Scientific interest in marine omega-3s developed considerably in the
1970s, with the study of diets rich in marine foods. Subsequent research has gradually clarified the distinct roles of
EPA in lipid signalling and
DHA in the structure of brain and visual membranes.
Who is this product for?Oméga 3 Marin may be particularly suitable for:
• people who eat
little oily fish such as sardines, anchovies, mackerel, herring or salmon;
• those wishing to have a
clearly quantified intake of EPA and DHA;
• people seeking
nutritional support for heart function;
• those wishing to maintain
normal brain function and vision with the full daily serving;
• people who prefer a
marine source that directly supplies EPA and DHA rather than a plant precursor such as ALA;
• those wishing to choose between a
short course and regular supplementation depending on their dietary habits.
Ingredient synergyEPA and DHA belong to the same family of fatty acids, but their roles are not identical.
•
EPA is primarily involved in the
production of lipid messengers that contribute to the body’s normal responses and cardiovascular function.
•
DHA is mainly a
structural component of membranes, with a particularly high presence in the brain and retina.
• The
EPA–DHA combination is primarily responsible for
supporting heart function.
•
DHA more specifically provides the benefits related to
normal brain function and the maintenance of normal vision.
The ratio of
540 mg of EPA to 360 mg of DHA gives the formula a predominantly EPA profile while maintaining an amount of DHA above the
daily threshold of 250 mg in a full serving.
Taking the product with meals, as recommended by Waybio, is consistent with its lipid nature: the presence of a meal
promotes digestion of the oil by bile and digestive enzymes.
What does the science say?In 2013, a team at Pennsylvania State University in the United States studied how different doses of EPA and DHA
were incorporated into red blood cell membranes.
The trial was
randomised, double-blind and placebo-controlled. It included healthy women and men aged
20 to 45, with a body mass index between 20 and 30. Participants ate little or no oily fish—fewer than four servings per month—and did not take omega-3 supplements.
In total,
125 people were allocated to the groups, and
115 completed the intervention and were included in the final analysis.
For
approximately five months, participants received one of the following amounts daily:
•
0 mg of EPA and DHA, with soybean oil used as a placebo;
•
300 mg of EPA and DHA;
•
600 mg of EPA and DHA;
•
900 mg of EPA and DHA;
•
1,800 mg of EPA and DHA.
The omega-3s were supplied by a
fish oil in triglyceride form. Participants took
six identical capsules per day, with food.
The researchers measured the
omega-3 index, meaning the proportion of EPA and DHA incorporated into red blood cell membranes. The average initial value was
4.3%.
The omega-3 index increased
in proportion to the dose received, with a
statistically significant relationship (p < 0.0001). In the group receiving
900 mg of EPA and DHA per day, the same amount as the maximum intake of this product, the index increased by approximately
75%. Its final median value reached
7.6%, while no notable change was observed with placebo.
The dose of EPA and DHA alone explained
68% of the variation in response. When weight, initial value, age, sex and physical activity were also taken into account, the model explained
78% of the differences between participants.
This study shows that a daily intake of
900 mg of EPA and DHA, the same amount as in Oméga 3 Marin, can
markedly increase their presence in cell membranes in adults who eat little oily fish. It directly illustrates the
gradual incorporation of these fatty acids into the body.
Full reference:Flock MR, Skulas-Ray AC, Harris WS, Etherton TD, Fleming JA, Kris-Etherton PM. “Determinants of Erythrocyte Omega-3 Fatty Acid Content in Response to Fish Oil Supplementation: A Dose–Response Randomized Controlled Trial.”
Journal of the American Heart Association. 2013;2(6).
DOI: 10.1161/JAHA.113.000513 – PubMed.
Heart and circulation
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